Global Genomic Surveillance Standard

Pango Network

Phylogenetic Assignment of Named Global Outbreak Lineages

The definitive nomenclature system for tracking SARS-CoV-2 evolution. Trusted by researchers, public health agencies, and laboratories in over 100 countries for accurate real-time lineage classification.

Open Source
Peer Reviewed
WHO Recognized
15M+
Sequences Analyzed
100+
Countries
3,800+
Pango Lineages
2,500+
Citations
About the Nomenclature System

What are Pango Lineages?

Pango lineages provide a systematic, hierarchical nomenclature for naming and tracking the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. This naming system is essential for epidemiological tracking, public health responses, and vaccine development.

Notable SARS-CoV-2 Lineages Through Time

B.1.1.7
Alpha
Dec 2020
B.1.617.2
Delta
May 2021
BA.1
Omicron
Nov 2021
XBB.1.5
Kraken
Jan 2023
JN.1
Current
2024

Hierarchical Naming

Lineages are named hierarchically (e.g., BA.2.86.1), clearly showing evolutionary relationships between variants.

Global Standard

The internationally recognized system used by WHO, public health agencies, researchers, and media worldwide.

Real-time Updates

Continuously updated as new variants emerge and are characterized by our international committee of experts.

Quality Assured

Every lineage designation undergoes rigorous review following strict epidemiological and phylogenetic criteria.

Open Source Software

Our Bioinformatics Tools

A comprehensive suite of open-source tools for SARS-CoV-2 genomic surveillance, lineage assignment, and outbreak investigation.

terminal
# Install Pangolin via conda (recommended)
$ conda install -c bioconda pangolin
# Or install via pip
$ pip install pangolin
# Analyze your sequences
$ pangolin your_sequences.fasta --outfile results.csv
# Example output:
Sample_001: JN.1.1.1 (probability: 0.998)
Sample_002: KP.3.1.1 (probability: 0.995)
Sample_003: JN.1.18 (probability: 0.992)
Real-time Monitoring

Variants of Concern Reports

Stay informed with our comprehensive reports on SARS-CoV-2 variants. Track global distribution, mutation profiles, and emerging lineages with data updated regularly from genomic surveillance networks worldwide.

Global Distribution Maps
Mutation Analysis
Trend Forecasting
Weekly Updates

Current Global Distribution

Based on recent submissions

Live Data
KP.3.1.1+8%
42%
JN.1.18+3%
23%
LB.1+12%
15%
KP.2.3-2%
11%
Other
9%

Data represents global distribution estimates. Regional variations may apply.

Trusted by Leading Institutions

Collaborating with research institutions and public health agencies worldwide

Wellcome Sanger InstituteUK Health Security Agency
Peer-Reviewed Research

Key Publications

The foundational research behind the Pango nomenclature system

Nature Microbiology2020

A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

Rambaut A, Holmes EC, O'Toole Á, et al.

The foundational paper establishing the Pango nomenclature system for tracking SARS-CoV-2 evolution during the COVID-19 pandemic.

Virus Evolution2021

Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool

O'Toole Á, Scher E, Underwood A, et al.

Describing the methods and algorithms behind the Pangolin tool for automated lineage assignment of SARS-CoV-2 sequences.

Ready to classify your sequences?

Upload your SARS-CoV-2 genome sequences to get instant Pango lineage assignments, quality metrics, and detailed analysis reports.

Trusted by researchers and public health agencies worldwide

1.2k+ GitHub Stars
500k+ Monthly Users
100+ Countries